Maintains strong bones. Supports healthy bone density and bone matrix. Promotes healthy bone marrow. Supports healthy immunity and healthy inflammation balance. Activates genes that produce healthy bone collagen. Osteo-MK4® K2+D3 provides the clinical trial dose of bioidentical MK4 with the synergy of D3 to promote healthy bone density and maintain strong bones. The evidence-based formula is backed by more than 30 years of research into the health benefits of MK4, vitamin D3, and calcium. MK4 is the most-studied form of vitamin K2 for bone health. MK4 activates genes that promote the creation of osteoblasts, reduces RANKL activity, which is associated with improved bone health, activates genes involved in bone collagen formation, enhances the ability of vitamin D to add minerals to bone, promotes healthy bone stem cell production, supports healthy bone density, and maintains bone strength.Three options to choose from Per day, each product provides the clinical trial dose of MK4 (45 mg/day) with 2000 IU (50 mcg) of vitamin D3. However, since not everyone needs the same amount of calcium as a dietary supplement, or any additional calcium at all, Dr. Neustadt created three versions of the product. This way, you can customize the choice based on each person’s unique needsOsteo‑K® with 1000 mg/day of calcium (as calcium citrate), is for people who need more calcium as a dietary supplement. Osteo‑K Minis with 400 mg/day of calcium (as calcium citrate). Osteo‑MK4, NBI’s calcium-free version.

WARNING: Do not take this product if you are taking anticoagulant medication (eg, warfarin). Vitamin K interferes with warfarin.