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††USA Functional Medicine MDs, DOs, NDs, DCs and Nutrition Professionals surveyed in 2025 for Designs for Health. B-Supreme is a powerful combination of B vitamins supplied mostly in their coenzymated forms, so that the body does not have to phosphorylate them to be used in biochemical reactions. This formula also includes the patented folate derivative Quatrefolic®, which is an innovative form of folate that has demonstrated high bioavailability, solubility, and long-lasting stability. Trimethylglycine (TMG) and choline are also included to support methylation.
Serving size: 1 Capsule
Servings per container: 60

Ingredient

Quantity

d-Biotin

2000 mcg

D-Calcium Pantothenate

100 mg

Quatrefolic® [6S]-5-methyltetrahydrofolate, glucosamine salt

340 mcg

Niacinamide

50 mg

Riboflavin

50 mg

Riboflavin-5-Phosphate

-

Thiamin HCI

100 mg

Methylcobalamin

250 mcg

Pyridoxine HCl

50 mg

Pyridoxal 5 phosphate

-

TMG

200 mg

Choline Dihydrogen citrate

30 mg

Other Ingredients: Cellulose (capsule), stearates (vegetable source), silicon dioxide.

Gluten free
Dairy free
Milk free
Non-GMO


Suggested Use:
Take 1 capsule per day or as directed by your health-care practitioner

Serving Size: One Capsule

Amount Per Serving
Thiamin ... 100mg
(Vitamin B-1)(as Thiamin HCl)
Riboflavin ... 50mg
(Vitamin B-2)(as Riboflavin and Riboflavin-5-Phosphate)
Niacin ... 50mg NE
(Vitamin B-3)(as Niacinamide)
Vitamin B-6 ... 50mg
(as Pyridoxine HCl and Pyridoxal-5-Phosphate)
Folate ... 340 mcg DFE
(as Quatrefolic® [6S]-5-methyltetrahydrofolate. glucosamine salt)
Vitamin B-12 ... 250 mcg
(as Methylcobalamin)
Biotin ... 2000 mcg
(as d-Biotin) 
Pantothenic Acid ... 100mg
(as d-Calcium Pantothenate)
Choline … 30mg
(as Choline Dihydrogen Citrate)
Trimethylglycine ... 200mg
(TMG)

Other Ingredients: Cellulose (capsule), stearates (vegetable source), silicon dioxide.

NOTICE Color, size or shape may appear different between lots. Store at room temperature. Keep out of reach of children.

Enhanced testing

How was this product tested?

At Emerson Ecologics, every brand meets our elevated quality standards. But we don’t stop there. As an added layer of assurance, select products from popular or problematic categories are subjected to enhanced testing by independent third-party labs to confirm potency and purity claims, giving you more trust in the products you recommend. Brands cannot pay for inclusion in Enhanced Testing or to receive an “Enhanced Testing” badge, ensuring that decisions remain clinically-focused and unbiased.

Learn more about the testing methods

B-Supreme

Designs for Health

Emerson Item Code

BSP60

Vendor Item Code

BSP060

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